A Bit about Gout

Todays post is about Gout.

Scott and I were recently discussing this condition that affects many people. There are many theories around what it is and how it is contracted.

So, here are some facts.

Gout was historically known as “the disease of kings” or “rich man’s disease”. It has been recognised at least since the time of the ancient Egyptians.

Gout affects about 1 to 2% of the Western population at some point in their lives. It has become more common in recent decades. This is believed to be due to increasing risk factors in the population, such as metabolic syndrome, longer life expectancy, and changes in diet

What is Gout?

Gout is actually a form of inflammatory arthritis caused by crystals that form in and around the joints. The crystals result from high levels of urate in the body. It is a condition caused by a build-up of uric acid and the body does not flush out the crystals fast enough. This build-up usually affects your feet. If you have gout, you’ll probably feel swelling and pain in the joints of your foot, particularly your big toe. Sudden and intense pain, or gout attacks, can make it feel like your foot is on fire.

What is Urate?

Urate is found in all people, in small amounts in our blood. Our bodies make it every day by breaking down natural substances called purines. Purines are found in our bodies’ cells, as well as some of the foods we eat. Our kidneys usually remove any excess urate from our blood into our urine. However, people with gout have higher-than-normal amounts of urate in their bodies. This can be a result of:

  • our bodies producing too much urate and/or
  • the kidneys being unable to get rid of it quickly enough (this is the main reason for high urate levels in more than nine out of ten people with gout).

If urate levels remain high, it starts to form small crystals in and around the joints. These crystals form slowly, over months or even years, usually without any symptoms. A gout flare up occurs when the body’s immune system attacks the crystals. The crystals still remain in the joint(s) even after the pain settles.

You’re more likely to get gout if you:

*are a middle-aged man or postmenopausal woman

*have parents, siblings, or other family members with gout

*drink alcohol

*take medications such as diuretics and cyclosporine

*if you have a kidney or thyroid problem, or an inherited disorder, can make it harder for your body to remove excess uric acid.

In some people with gout, diet is the cause.

How can diet contribute?

Certain foods are naturally high in purines, which your body breaks down into uric acid. Most people don’t have a problem with high-purine foods. But if your body has trouble releasing excess uric acid, you may want to avoid certain foods and drinks, such as some red and organ meats, certain seafood and alcohol.

Some sugar-sweetened beverages and foods containing fructose can also be problematic, even though they don’t contain purines.

There is however, evidence from studies suggesting that certain foods help can reduce uric acid levels in the body. They are – tart cherries, magnesium, ginger, apple cider vinegar, celery, nettle tea, dandelion and milk thistle seeds.

But simply eating these foods may not be enough to control gout

If left untreated, gout can eventually lead to arthritis. Hard lumps called tophi can eventually develop in your joints and the skin and soft tissue surrounding them. These deposits can permanently damage your joints.

If you think your may be suffering with gout, it is important to seek advise from your chosen health professional.

Moving forward

The only way to diagnose gout with certainty is by your doctor finding urate crystals in fluid taken from your joint. Uric acid levels can also be measured by blood tests, however these are not always accurate. However, blood tests are useful in ruling out other causes for your symptoms, such as joint infections or other forms of arthritis.

The treatment plan recommended will depend on the stage and severity of your gout.

I hope you found this information helpful.

Till the next post,

 

Live clean n Prosper

Sources – Healthline, Arthritis Australia, Wikipedia

What is GABA?

Today’s post is about GABA.

A friend and I were talking about this recently, so as usual, I’ve done some research so I can share some information with you.

So, first of all what is GABA?

GABA is the acronym for Gamma-Aminobutyric acid, which is an amino acid that is produced naturally in the brain. It is a neurotransmitter, or chemical messenger, in the brain.

GABA’s big role in the body is to help the body and brain to relax. It promotes feelings/sensations of calm and tiredness. The brain naturally releases GABA at the end of a day to promote sleepiness and allow a person to rest.

It does this by blocking specific signals in the central nervous system, slowing down the brain. This provides a protective and calming effect on the brain and body. Which in turn, helps to slow down the heart rate and breathing, as well as relaxing muscles.

Too much or too little

Too much GABA means that there is not enough brain activity. This can lead to hypersomnia or daytime sleepiness.

At the other end of the scale, a lack of GABA leaves your central nervous system with too many neuronal signals. This can cause conditions like epilepsy, seizures or mood disorders.

For those who have low levels of GABA, symptoms may include feelings of anxiety, stress and worry.

Because alcohol targets GABA receptors and mimics the effect of this neurotransmitter, helping to relax the mind and body.  Some people find they have alcohol cravings. While alcohol may help in the short term, the negative side effects of too much alcohol outweigh the temporary feelings of calm and relax.

There are medications designed to interact with the GABA receptors in the brain, to achieve certain effects. These are typically prescribed to help with pain relief, stress and anxiety reduction, lower blood pressure, and improved sleep. These medications include benzodiazepines, antidepressants, and anti-seizure medications.

GABA and diet

Gamma-Aminobutyric acid does not occur naturally in foods. However, a variety of foods contain flavonoids that influence GABA levels and how it works in the brain.

These include varieties of green, black, and oolong tea, fermented foods including kimchi, miso, kefir, yogurt, and tempeh. Other foods that may boost production are;

  • whole grains, fava beans, soy, lentils, and other beans;
  • nuts including walnuts, almonds, and sunflower seeds;
  • fish including shrimp and halibut;
  • and citrus, tomatoes, berries, spinach, broccoli, potatoes, and cocoa.

A number of natural supplements also affect GABA activity to help relieve stress and anxiety, promote a balanced mood, and help with sleep. These include;

  • valerian and hops
  • magnesium
  • L-theanine
  • L-arginine
  • kava
  • passionflower
  • American ginseng.
What about supplements?

GABA is also available as a supplement. These supplements are often taken to treat high blood pressure, stress and anxiety, and sleep.

However, scientists have not been able to prove the positive effects of GABA supplementation or what kind of risks it might pose, so their use may have limited effectiveness.

Before deciding to use a GABA supplement, it may be a good idea to seek advise from a health professional.

Till the next post,

Live clean n prosper

(Sources – web MD  – Food for the Brain Foundation –  McGill OSSNews, Medical-Life Sciences – )